Active Ingredients: Amoxicillin
Primary Outcomes HP eradication rate calculated from negative 13 C-urea breath tests. Eligibility Criteria Male or female participants from 18 years up to 65 years old. Efficacy analysis will be based on H. Such margin was selected in accordance with previously published trials performed with the reference combination.
Chi-square test and Student's t-test will be used to compare both groups regarding baseline data, eradication rate, adverse events and biochemical results for safety analysis.
What is Amoxil? Amoxil amoxicillin is a penicillin antibiotic that fights bacteria. Amoxil is used to treat many different types of infection caused by bacteria, such as tonsillitis, bronchitis, pneumonia, and infections of the ear, nose, throat, skin, or urinary tract.
Amoxil is also sometimes used together with another antibiotic called clarithromycin Biaxin to treat stomach ulcers caused by Helicobacter pylori infection.
This combination is sometimes used with a stomach acid reducer called lansoprazole Prevacid. Before using Amoxil, tell your doctor if you are allergic to cephalosporins such as Omnicef, Cefzil, Ceftin, Keflex, and others.
Also tell your doctor if you have asthma, liver or kidney disease, a bleeding or blood clotting disorder, mononucleosis also called "mono", or any type of allergy.
Amoxicillin can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control such as a condom, diaphragm, spermicide to prevent pregnancy while taking this medicine.
Take this medication for the full prescribed length of time. Both groups will receive the treatment for 10 days.
Antibiotics will be prescribed after meals, whereas the proton-pump inhibitor will be taken in a fasting condition. No other medication will be allowed until the end of the treatment.
Eradication of H. No further medication will be allowed during the four weeks preceding the 13 C-UBT. Regarding safety assessment, blood samples will be collected in a central laboratory following signature of the informed consent and before treatment beginning.
Pregnancy and breast-feeding Check with your doctor before you take this medicine if you are pregnant or breast-feeding.
The maximum daily dose is 6 g given in divided doses. The following are the usual adult dosages for preventing infection during dental procedures and other surgery: If a general anaesthetic is not used, 3 g given orally one hour before surgery and another dose six hours later if necessary If a general anaesthetic is used, 3 g given orally four hours before anaesthesia and 3 g six hours after the initial dose Children It is recommended that children be given Amoxicillin as a suspension instead of as capsules.
Children weighing more than 40 kg should be given the usual adult dosage. Children weighing less than 40 kg who are able to swallow capsules: All doses are worked out depending on the child s body weight in kilograms.
Your doctor will advise you how much medicine you should give to your baby or child. The usual dose is 40 mg to 90 mg for each kilogram of body weight a day, given in two or three divided doses.
It is not normally necessary to arrange to have a dose in the middle of the night, unless your doctor has told you to do so.