Active Ingredients: Ciprofloxacin
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Prolongation of the QT Interval Some fluoroquinolones, including Ciprofloxacin, have been associated with prolongation of the QT interval on the electrocardiogram and cases of arrhythmia. Cases of torsade de pointes have been reported during postmarketing surveillance in patients receiving fluoroquinolones, including Ciprofloxacin.
Musculoskeletal Disorders in Pediatric Patients and Arthropathic Effects in Animals Ciprofloxacin is indicated in pediatric patients less than 18 years of age only for cUTI, prevention of inhalational anthrax post exposure, and plague [see Indications and Usage 1.
Histopathological examination of the weight-bearing joints of these dogs revealed permanent lesions of the cartilage. Therefore, avoid excessive exposure to these sources of light.
Discontinue Ciprofloxacin if phototoxicity occurs [see Adverse Reactions 6.
Development of Drug Resistant Bacteria Prescribing Ciprofloxacin tablets in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.
Interference with Timely Diagnosis of Syphilis Ciprofloxacin has not been shown to be effective in the treatment of syphilis. Perform a serologic test for syphilis in all patients with gonorrhea at the time of diagnosis.
Perform follow-up serologic test for syphilis three months after Ciprofloxacin treatment. Crystalluria Crystals of Ciprofloxacin have been observed rarely in the urine of human subjects but more frequently in the urine of laboratory animals, which is usually alkaline [see Nonclinical Toxicology 13.
Crystalluria related to Ciprofloxacin has been reported only rarely in humans because human urine is usually acidic.
Do not give this medicine to a child without medical advice. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant. You should not breast-feed while using this medicine.
How should I take ciprofloxacin? Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Take ciprofloxacin with water, and drink extra fluids to keep your kidneys working properly. Shake the oral suspension liquid for 15 seconds just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup.