Active Ingredients: Doxycycline
In this case, you will be giving 20 milliliters for your 1,000 lb horse.
When working with paste products: Most paste products come in syringes with the dose rate marked on the plunger. If you are calculating the correct dosage for your horse, simply use the basic calculation formulas given above and apply them to the dose rate marked on the plunger.
Note that pills and tablets should not be given to foals and small ponies because of their small esophagi. Horses with a history of choke should not be given large pills or boluses.
In all cases, it is best to have your veterinarian prescribe all medications and drugs for your horses.
The incubation period is approximately 10 days range 4—19 days 8. Leptospirosis is an acute febrile illness with nonspecific clinical signs and symptoms and a variable clinical course.
Clinical manifestations include fever, malaise, myalgia, meningism, and conjunctivitis, as well as anorexia, abdominal pain, nausea, and vomiting 1 — 3.
Initial signs of serious infection can include jaundice, hemorrhage, and hepatosplenomegaly. The most severe form of leptospirosis can occur as Weil syndrome with hepatic and renal failure or massive pulmonary hemorrhage; both forms can progress rapidly to death if untreated 1 — 3.
Leptospirosis is thought to be the most widespread zoonotic disease in the world 10.
Most reported cases occur in men, most likely due to greater occupational exposure 11. Recent outbreaks associated with water sports and recreation include 68 of 304 athletes participating in a 2-week adventure sport race, the Eco-Challenge-Sabah, in Borneo, Malaysia 12, and 74 of 639 triathletes in 1998 races in Wisconsin and Illinois, in the largest known outbreak of leptospirosis in the United States 13.
Leptospirosis in the United States The reported incidence of leptospirosis is 100—200 cases per year in the United States 2, 14, with most 50—100 cases occurring outside the continental United States in Hawaii 15.
Never take an extra dose to make up for a forgotten one.
You could also ask your pharmacist for advice on other ways to remember your medicines. What if I take too much?
Accidentally taking an extra dose of doxycycline is unlikely to harm you. Speak to your pharmacist or doctor if you're worried or you take more than 1 extra dose.