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Discussion This study is the first large-scale surveillance of the prevalence of macrolide and fluoroquinolone resistance-associated mutations in M.
Previously, only one minor study including 47 M.
Consequently, there might have been a few cases of treatment failures in the examined material, creating a limited bias in the prevalence of mutations.
Conclusions The prevalence of macrolide and fluoroquinolone resistance-associated mutations in M. Despite the relatively low rates of macrolide and fluoroquinolone resistance in these countries, antimicrobial resistance surveillance would be valuable, and M.
Unfortunately, the importance of a number of mutations in the 23 S rRNA gene and particularly the parC gene remains unknown. This calls for prioritizing culture of samples with such mutations in order to associate mutations with phenotypic resistance and treatment outcome.
Ultimately, novel antimicrobials for treatment of M. Formal analysis: ES MU. Methodology: ES MU.
Software: Not applicable. Writing — original draft: ES MU.
References 1. Mycoplasma genitalium: from chrysalis to multicolored butterfly.
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