Active Ingredients: Doxycycline
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Doxycycline belongs to a group of antibiotics called tetracyclines. Malaria is an important cause of death in tropical countries.
Malaria control requires an integrated approach, including prevention, prompt diagnosis and treatment with effective antimalarial drugs. ACTs are now recommended by WHO as the first line treatment of uncomplicated falciparum malaria in all endemic areas.
Resistance to antimalarial drugs has been documented in all classes of antimalarials including artemisinin derivatives and it is a major threat to malaria control. When given the second time in a different combination, he had recrudescence with recurrence of fever twelve days after the medicines were stopped.
Also another interesting fact that emerged in this case was the persistent diagnostic dilemma due to negativity of malarial parasite on microscopy as well as by RDT, optiMAL based on Plasmodium lactate dehydrogenase LDH.
There are concerns about availability of fake drugs in the market which lead to treatment failure and propagate resistance. Artemisinin compounds used in our case both the times were from reputed drug firms in doses recommended as per the body weight of the patient and were tolerated well.
The question that remains to be answered is whether this case report is heralding the beginning of ACT resistant malaria in India; this needs further investigation on a large scale in malaria endemic areas.
References WHO guidelines for treatment of malaria. Geneva — World health organisation,. This will give you a general idea of what you need to consider for your trip Click here for more information on routine, recommended and required vaccinations How can I prepare for travel to high altitude?
There is no way of predicting your response to travel to altitude either trekking, bus or flights to cities e. Even the experienced sherpa or triathlete can develop alttitude sickness on his first season climb.
The risk of altitude illness is entirely based on the rate of ascent, and not the overall altitude reached. It is remarkable how many travellers believe that a 'headache' at altitude is normal, it is not!
If you are carrying altitude medication, always carry a package insert in the actual medication container to refer to so you know when, how to use and how to titrate so you achieve the optimum therapeutic dose with the least side-effects.
Preventative medication include gingko, acetazolomide and dexamethasone. The treatment of altitude sickness is descent, however some of drugs can be used as treament.
No medication is as effective as slow, graded ascent and with good acclimatization. This leads me to believe that the wholesalers are coming out way ahead on this trend! La siento bastante irritada especialmente al aplicarme mi serum habitual y el protector solar de 50!
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This is called the Koebner phenomenon.
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