Active Ingredients: Norfloxacin
Do not pass it on to others. Inflammation of the liver with jaundice yellowing of the skin or whites of the eyes commonly occurs.
Stop treatment and contact your doctor if you experience signs and symptoms of liver problems such as loss of appetite, jaundice, dark urine, itching or sensitivity to pressure in the abdominal cavity.
If you develop the rare side effect of severe and persistent diarrhoea whilst you are taking your tablets or after stopping your tablets you should consult your doctor.
In rare cases seizures occur. If fits occur, stop taking this medicine. You can also report side effects directly via the Yellow Card Scheme at.
By reporting side effects you can help provide more information on the safety of this medicine. How to store Norfloxacin 400 mg Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the label and the carton.
The expiry date refers to the last day of that month. Store in the original package.
Keep the blister in the outer carton. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
Contents of the pack and other information What Norfloxacin 400 mg contains These tablets contain 400 mg norfloxacin as the active substance.
This might increase the risk of methotrexate toxic reactions.
Current or past treatment with oral corticosteroids is associated with an increased risk of Achilles tendon rupture, especially in elderly patients who are also taking the fluoroquinolones.
Careful monitoring and supportive treatment, monitoring of renal and liver function, and maintaining adequate hydration is recommended by the manufacturer. At the respective doses, mean peak serum and plasma concentrations of 0.
The effective half-life of norfloxacin in serum and plasma is 3—4 hours. Steady-state concentrations of norfloxacin will be attained within two days of dosing.
Norfloxacin is least soluble at urinary pH of 7. Other companies initiated fluoroquinolone discovery programs in the aftermath of the publication of the norfloxacin patent.
Five adverse clinical experiences and six adverse laboratory experiences were noted. Only one of the former mild heartburn was thought to be drug related, and no adverse experience was considered serious or required discontinuation of treatment.
Take norfloxacin exactly as your doctor tells you to. The usual dose is one 400 mg tablet, taken twice a day.