Active Ingredients: Norfloxacin
Do not pass it on to others.
Drinking plenty of liquid can help prevent this occurring. If you develop severe and persistent diarrhoea whilst you are taking your tablets or after stopping your tablets you should consult your doctor.
Other medicines and Norfloxacin 400 mg Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
You must tell your doctor if you are taking other medicines that can alter your heart rhythm: medicines that belong to the group of anti-arrhythmics e. Multivitamins, products containing iron or zinc, antacids or sucralfate should not be taken at the same time as this medicine.
This medicine should be taken either 2 hours before or at least 4 hours after such products. Pregnancy, breast-feeding and fertility If you are pregnant, planning a family or breast-feeding, tell your doctor before taking this medicine, as it is not recommended for use under these conditions.
How to take Norfloxacin 400 mg Always take your medicine exactly as your doctor or Pharmacist has told you. You should check with your doctor or pharmacist if you are not sure.
The usual dose in adults is 1 film-coated tablet 400 mg norfloxacin twice daily.
The recommended dose is 1 film-coated tablet 400 mg norfloxacin once daily.
Swallow the tablets with a glass of water at least one hour before or two hours after a meal or drink of milk. CHMP stated that doctors should not prescribe oral norfloxacin for complicated pyelonephritis and should consider switching patients already taking oral norfloxacin for this type of infection to an alternative antibiotic.
Contraindications As noted above, under licensed use, norfloxacin is also now considered to be contraindicated for the treatment of certain sexually transmitted diseases by some experts due to bacterial resistance.
Patients taking any of these drugs concomitantly with norfloxacin should be carefully monitored.
Pregnancy Norfloxacin has been reported to rapidly cross the blood-placenta and blood-milk barrier, and is extensively distributed into the fetal tissues.
For this reason norfloxacin and other fluoroquinolones are contraindicated during pregnancy due to the risk of spontaneous abortions and birth defects. The manufacturer only recommends use of norfloxacin during pregnancy when benefit outweighs risk.
Ciprofloxacin is being licensed for the treatment of Complicated Urinary Tract Infections and Pyelonephritis due to Escherichia coli and Inhalational Anthrax post-exposure and levofloxacin was recently licensed for the treatment of Inhalational Anthrax post-exposure.
Thus, the preferred initial treatment for refractory ascites is large-volume paracentesis with albumin replacement.
TIPS as initial therapy should be evaluated on a case-by-case basis and reserved for patients less than 70 years old, with preserved liver function, without hepatic encephalopathy or severe cardiopulmonary disease, who require very frequent paracentesis, or in whom ascites cannot be adequately eliminated by paracentesis.
Listing of these, including any guidelines for monitoring side effects.
If it fails to drop, antibiotic resistance should be suspected and modification in therapy be implemented.
Antibiotics are changed depending on results from cultures.
Response to therapy should be monitored by clinical signs, white blood count and PMN polymorphonuclear leukocyte count in the ascitic fluid.