Active Ingredients: Norfloxacin
Pre-trial haematological, renal and liver function tests were done.
Urine culture and colony counts were repeated on 3 rd or 4 th day, 7 th day and after every two weeks for 6 weeks. Haematological, renal and liver function tests were repeated after 6 weeks. Common presenting features were dysuria 34, lumbar pain 31, in-creased frequency 26, fever 11 and haematuria 10.
Thirty one 67. The causative micro-organisms isolated were E.
Coli 82. Twenty four patients had uncomplicated and 22 complicated UTI associated with calculus disease, diabetes meffitus, urethral stricture and other urological problems. Pre- and post- trial haematological, and liver and kidney function tests remained unchanged in almost all cases.
The drug was well-tolerated except by one patient who developed gastrointestinal symptoms: flatulence, loss of appetite, epigastric pain and vomiting which improved after withdrawal of the drug.
Nine patients had a relapse one to six weeks after stopping the drug. The organisms were still sensitive to Norfioxacin except in one patient.
All patients with relapse had complicated UT. One female patient was given Norfioxacin in 5 th month of pregnancy with no after effects on mother or foetus.It is amazing to me that my daughter at one time would.
Four patients with moderately impaired kidney functions were given Norfloxacin 400 mg 12 hourly for 7 days. We look forward to continuing to serve and engage with them as well as other stakeholders in the future.
Reema Mohindra I am text block. Click edit button to change this text.