Active Ingredients: Orlistat
Treatment groups were compared using descriptive statistics with respect to adverse events and vital signs.
The mean apparent mineral absorption and balance determined during the last 7 d of treatment was used as the primary between-group comparisons to test the influence of orlistat on mineral metabolism.
An unpaired t-test was used to determine significant treatment differences.
A paired t-test was used to determine significant differences within treatments. All men completed the study. As expected, groups did not differ in age, because the subjects who were assigned to the placebo and treatment groups were initially matched for age.
Fecal excretion. TABLE 3 Dietary fat excretion during 7 d of treatment with orlistat 120 mg or placebo tid and a hypocaloric diet after a 14-d equilibration period to treatment and a hypocaloric diet in obese men 1.
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