Active Ingredients: Azithromycin
View All Indications and Usage for Zithromax Zithromax is a macrolide antibacterial drug indicated for the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below.
Usage To reduce the development of drug-resistant bacteria and maintain the effectiveness of Zithromax and other antibacterial drugs, Zithromax should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteria.
Genitourinary: Monilia, vaginitis, and nephritis. Nervous System: Dizziness, headache, vertigo, and somnolence.
General: Fatigue. Allergic: Rash, photosensitivity, and angioedema.Strengths: 250 mg, 500 mg, 600 mg Brand: Zithromax Strengths: 250 mg, 500 mg For bronchitis Adult dosage ages 18 years and older Typical dosage is 500 mg once per day for 3 days.
Chronic therapy with 1200 mg weekly regimen The nature of adverse reactions seen with the 1200 mg weekly dosing regimen for the prevention of Mycobacterium avium infection in severely immunocompromised HIV-infected patients were similar to those seen with short-term dosing regimens.
Five percent of patients experienced reversible hearing impairment in the pivotal clinical trial for the treatment of disseminated MAC in patients with AIDS.
Hearing impairment has been reported with macrolide antibiotics, especially at higher doses.
Discontinuations from treatment due to laboratory abnormalities or adverse reactions considered related to study drug occurred in 8 of 88 9.
Single 1 gram dose regimen Overall, the most common adverse reactions in patients receiving a single-dose regimen of 1 gram of Zithromax were related to the gastrointestinal system and were more frequently reported than in patients receiving the multiple-dose regimen.
Postmarketing Experience The following adverse reactions have been identified during post approval use of azithromycin. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
Cardiovascular: Arrhythmias, including ventricular tachycardia, and hypotension. There have been reports of QT prolongation and torsades de pointes.
General: Asthenia, paresthesia, fatigue, malaise, and anaphylaxis. Genitourinary: Interstitial nephritis, acute renal failure, and vaginitis. Hematopoietic: Thrombocytopenia.